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Abia Varsity announces Discovery of HIV/AIDS cure by its Professor, Maduike Ezeibe

BellaNaija.com

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Prof. Maduike Ezeibe

Prof. Francis Otunta, the Vice Chancellor, Michael Okpara University of Agriculture, Umudike, Abia state, has announced the discovery of a drug for the treatment and cure of HIV/AIDS by the institution.

Otunta told newsmen at the university campus on Wednesday that the finding followed years of scientific research by the institution.

He said that the breakthrough was made by Prof. Maduike Ezeibe, a researcher in the university.

According to him, Ezeibe had presented the drug to the University management, Senate and Council, where he explained the processes he went through to arrive at his finding.

The VC also said that Ezeibe had equally presented the drug to his colleagues in the medical field and nobody had contradicted his finding.

“Prof. Ezeibe is a researcher in Veterinary Medicine and one may wonder how he discovered a drug to cure a human ailment,” he said.

He commended Ezeibe for the breakthrough, saying: “He has brought honour to the University and we are proud of him.”

Otunta said that the university was in the process of mass producing the drug for further clinical trials on persons living with HIV/AIDS in the country.

Ezeibe, who is a professor of Veterinary Medicine and Clinical Virology, said that the drug was produced with Aluminum Silicate and Magnesium Silicate (Synthetic Aluminum-Magnesium Silicate).

He said that the two minerals “are already in use as medicines for the treatment of various animal and human diseases”.

He said that 10 persons living with the disease, “who volunteered’’, were made to apply through their doctor to the VC.

“They were treated daily with the Medicinal Synthetic Aluminum-Magnesium Silicate (50 mg/kg),” he said.

Ezeibe said that the volunteers were subjected to monthly tests for viral loads and CD4-lymphocyte counts.

“With the antiviral effects of the medicine, its ability to reach all cells (as nanoparticles) and the lymphocytes, there is no more hiding place (sanctuary) for HIV,” he said.

He said that the medicine had been used to potentiate Ampicilin, Chloroquine, Piperazine and Sulphadimidin, among others, and could be a major foreign exchange earner for Nigeria, if approved by relevant authorities.

According to him, “local and international pharmaceutical companies will find the product as a veritable raw material”.

Ezeibe said that he presented the research findings to the World Virology Conference in Atlanta in 2015, and Antonio (Texas) in 2016.

Besides, he said that the results of the laboratory tests had been published in many international scientific journals, including the British Journal of Medicine and Medical Research, among several others.

He said that he is also about to sign a Memorandum of Understanding with a U.S.-based Scientific Research Publishing, publishers of World Journal of AIDS, for the publication of his book “How I came about the cure for HIV/AIDS”.

Ezeibe, who said that the medicine was patented in August 2014 in Nigeria, called on the Federal Government to help him to secure international patency for the drug.

He said: “If commercialised, the Medicinal Synthetic Aluminum-Magnesium Silicate would become an alternative for petroleum to the Nigerian economy.”

30 Comments

  1. RichyGame

    February 1, 2017 at 11:26 pm

    Not the first… yeah, sue me. But good.
    This has been stifled long enough. I guess other more important and revenue generating diseases are on board now. LoL.

    • Fleur

      February 2, 2017 at 4:27 am

      so I dont want to be a cynic because it is possible for his to discover a treatment and that will be a beyond stellar accomplishment for the continent. However Professor, here are my issues. Your Br. J. Med & Med. Res. article is a testtube assay (http://www.journalrepository.org/media/journals/BJMMR_12/2013/Dec/Ezeibe482013BJMMR7103.pdf). You dont make the leap in conclusions that you have made with a “clinical trial” of 10 people, no information on time of follow-up, no information on systemic titer values post-treatment in your small cohort, no controls (unexposed), no information on side effects of the drug administered (you know that they might have heavy metal poisoning from Al and serious bone calcium issues with Magnesium intake). I am curious about their kidney function because of the effect of heavy metals on the kidneys. You do not discuss your drug’s supposed mode of action – at least not in a scientific way. You are using nanoparticles – yes, they will get in everywhere but they will do both harm and good – at least the Aluminium since it is not needed in the body. So calm down and conduct a stronger study. There are many HIV cases to work with in Nigeria. Regarding the potentiation of effects of antibiotics – I can see where the combo you have prepared can have cytotoxicity especially since you are using nanoparticles. The question is does it have the same effect as cancer treatment, which will kill all cells good and bad but result in a cure in some cases? I know people have lined up to drink this concoction. Anyway, magnesium is a very powerful supplement – in a positive way.

    • RichyGame

      February 2, 2017 at 7:24 am

      Erm @Fleur, I guess the response wasn’t for me but from my layman vantage, you make a good point… I guess.

    • Sampson I. Onwuka

      January 21, 2018 at 12:12 am

      S.I Onwuka

      The three properties associated with Prof. Maduike Ezeibe’s Aluminum magnesium Silicate (AMS) for curing HIV is (1), AMS is lighter than HIV molecules- an argument that means that it has nano light weight property that can penetrate any cell in the body, (2) that it can reach any part of the body including the HIV sanctuaries (very important) through the mucus membrane with the help of glucose, (3), it has both negative and position charges, a property that I find interesting having personally and independently come up with the same conclusion that it is a neutral charged dense electron that has a chance of forming the right affinity with the positive HIV virus, CD4+, etc., and in so doing kill the virus or neutralize – may me a ready believer in Prof. Maduike Ezeibe theory – to a point that, (4) that AMS doesn’t any additional surprise to me for having the potential of stimulating the CD4s and B cells and in turn stimulate the HIV antibody, suggesting also to me that failures of the core-receptors necessary for the initial binding and penetration of the cells by HIV to manage a profligate b-cell is perhaps due to the collapse of a certain C3 during the primary interactive stage with the HIV, an immune region that AMS also ‘stimulate’, leads the arguments that C3 when fully functional can regulate b-cells profligate and in this case stimulate the body’s defenses, inhibit the many deaths and destruction of CD4s by NK CD8s.

      With these three, four, properties, there are degrees of reasons to accept that AMS is leading candidate in curing HIV and argument that rest on how we broach the subject of HIV and its curative, for a fact, the schools of vaccines since Robert Gallo has more than over shadowed the school of drug Agent, largely because of the failures of the primary enzymes in the body and signal cytokines to dictate infected cells on time and send official NK. In that, HIV is covered with human specific protein emanating from a Chromosome 16 CD43 with human sera for Siliac Acid hanging loose and unstable on the surface of the cell, argued by Arjit and Elizabeth Muchmore to be the acid that separate humans from other primates on account of sugar complex – meaning that our body’s immune and cell mediated defenses lies with with emphasis on HPA antigenic peptide, the Amino acids in the chain of HPA explains the mutation of Chromosome 23, Amino acid 23 – mutant on account of HIV with due respect to 22 for diabetics on account of the mutant insulin sugar – repaired by introducing insulin, and copied by scientist 23 for HIV – primarily useful in picking up a virus infected cell – to be repaired briefly by HPA 23 (Ammonium-21 tungsto 9 antimoniate) which was briefly the lovejoy of Chermann and French company, used extensively on Rock Hudson but ended in failure for what was lacking was a neutral agent capable of penetrating the sanctuaries and whacking the HIV virus by inhibiting the reverse transcriptase and protease of a virus called HIV when it is already in its sanctuary.

      It is not a new argument that AMS and C3 are useful points to consider given the body’s own ability to neutralize any drug sent to whack HIV, for now it seems that glycoproteins are human specific proteins that protect HIV from detection very early, to a point that we must know that once HIV through its attachment to core-receptors (achieved as I want you to believe through a dense anionic/cationic polymer, affinity) on the angles 41, 120, that it would be too late for the NK to react because CD8 like most drug agents do not penetrate the nucleus. CD8 are capable of killing any virus if they are dictated early, including HIV which when coated with glycoproteins may remain attached on the surface by CD4, CD5, and replicate inside the cell nucleus through protease and reverse transcriptase. It is here that I think we may truly consider if we are to look at the Prof. Ezeibe’s possible breakthrough.

      And speaking of reverse transcriptase, we can mention retrovirus and the difficulty in developing an assay for HIV. An argument on how the body responds to the infected cells is the basis on Peter Doherty’s career and may be off the point on the argument that Doherty 2013 “Pandemics’ in defining retroviruses mentions that “…the discovery that RNA tumor viruses use RT to insert their genetic information into the vertebrate genome earned U.S researchers Howard Temin and David Baltimore the 1975 Nobel prize for medicine.” A point that the retrovirus characteristic of HIV is one of the chief reasons why agent drugs are not potent to kill HIV unless, it has the ability to form an attachment first with the virus, as Rna sequences included in genome packaging (vertebra) may occasionally amount a degradation of ‘interferons type receptors for penetration’ of rotavirus, as if like HIV forming an initial attachment to CD4, glycoprotein before penetrating the cells, as if like Herpersvirus’s Glycoprotein b forming initial interaction with membranes in the specialized region fusion loops (FLS) before penetration of the cells, as if like Rubella Virus penetration of host cell membrane sphingomyelin and cholesterol before the cells, AMS or any gram neutral drug therapy capable of forming an attachment with HIV on the surface of the cells and as with AMS – capable of also penetrating cells, can essentially whack the HIV without relapse to vaccination and human immunologic assay.

      The reasons are many that the most some of the drugs discovered have done is to limit the life of HIV protein structure and perhaps, inhibit its re-production and in the process they hope end the life of virus or stop it from circulating. 1, Nucleoside Transcriptase inhibitors (NRTIs, or Nukes) ‘These drugs prevent the viral RNA from charging into DNA, by the use of an enzyme found in the cytoplasm of your host cells called reverse transciptase enzyme, and in disarray sources point to drugs Abacavir/ABC (Ziagen), Didanosine/ddi (videx), (2) Nucleotide Reverse Transcriptase Inhibitors > (Truvada, Tenofovir), (3) Non-nucleoside Transcriptase Inhibitors (nNRTIs), (4) Protease inhibitors, (5) Haart, are therapies that inhibit the profligate virus but do not like Aluminum Magnesium Silicate (AMS) kill the Virus, that the AMS inhibits is sufficient to consider a useful therapy like these inhitors, but as a Drug agent, AMS kills the virus in the cell, in its sanctuary and in its traces along the mucus membrane. It does this on account of one major property its neutral charge that stimulate HIV on one hand, CD4 on another hand, without increasing glucose, cell death and damage saving the early termination of infected cells, fat detonation>triglycerides….For this it open all kinds of argument on the need for vaccines, which relies on the antibodies of the antigenic peptides, nine of which is the regions of HIV genome, a deamination of any of the 9 genome, valin, gives us the idea of antibody cross-reactivity and perhaps transduction pathway or reduction which is signaling….

      In seems that since the days of Robert Gallo and Luc Montaignier, Jean Claude Cherman, Don Francis, Jonas Salk, Francis Sinnoussi, Charles Merieux, Robin Weiss etc., that developing a vaccine has displaced the emphasis on agent drug or immunogenic capable of handling the virus without the land of even AZT.

      As I have argued that ‘off the reel, that we trace the beginning of this emphasis on vaccine to the years leading to the polio vaccine, to a perhaps 1975 National Cancer Institute (Federick Cancer Research Institute) isolated cancer causing viruses including what we will known as HTLV (Human T-cell Leukemia virus) and part of the reason for isolating the virus is to create a cancer vaccine – a tradition that link us to Polio Age and the use of cancer patients for experiments by both Salk and Sabin, especially Sabin who later wanted to develop a live virus for cancer. HTLV was known to be identical to HIV, but there were other strains of the HTLV (HTLV III, LAV) that was believed to be the isolated AIDS virus by Luc Montaigner (through the ‘lymph nodes’ of the patient), Jean Chermann, Francis Sinnoussi and alternately Robert Gallo. 

      It is important to understand the story regarding Albert Sabin in developing live viruses for Polio vaccination and his working relationship to a certain Hilary Koprowski who worked in Stanleyville in Congo and who was the boss of a future Chairman of National Cancer Institute and expert in cancer, Robert Gallo. Robert Gallo was the boss of other cancer research scientists that will focus on Africa as the source of HIV, and the last known scientists associated with this theory is Beatrice Hahn and George Shaw. These group were known to have insisted that a certain Chimpanzee (SIV cpz) found in the South eastern boundary of Cameroon (approx. 50km north of Ouesso) is the likely source of HIV.

      I indulged some of the stories – which are gradually classic – because of over 30 vaccine programs have been launched and failed in Africa without Africans and for the record others, knowing about it. These faulty vaccine ended up giving the patients HIV and part of the reason why HIV has affected millions…. I wonder why Simon Flexner doesn’t seem to be mentioned anywhere in this whole evolution of Africa as home for vaccine, partly because of many primates (monkeys, Chimpanzees, Apes etc.,) he used and eventually euthanized depopulating primates in Africa. With Flexner and Rockefeller University, you realize the chain of erroneous tradition from Flexner, Tom River, Max Theiler, Isabel Morgan, and eventually Jonas Salk, Albert Sabin, Hilary Koprowski…..

      The vaccination In Africa was not based on science, it was based on tradition and a body of knowledge for over a century….

  2. A Real Nigerian

    February 1, 2017 at 11:31 pm

    Hahahaha!
    Igbos and Fraud, still a better love story than Twilight.

    • Ade

      February 2, 2017 at 2:19 am

      Desist from stereotyping an ethnic group. Grow up!

    • A Real Nigerian

      February 2, 2017 at 2:54 am

      But stereotyping is fun…

    • Ade

      February 2, 2017 at 4:03 am

      But stereotyping is fun? I guess it’s fun when black people are stereotyped as thieves? Grow up, be a beacon of change and not a part of the problem.

    • A Real Nigerian

      February 2, 2017 at 4:25 am

      “I guess it’s fun when black people are stereotyped as thieves?”
      Yes it is.

    • benjamin

      February 2, 2017 at 6:30 am

      Your Mother and Fraud.

    • benjamin

      February 2, 2017 at 6:31 am

      idiot

  3. Marian

    February 1, 2017 at 11:40 pm

    Read his paper and it was more of a hypothesis that has not been proven to be true.
    Next stage in my opinion should have been getting funding for a large sample size and following them for more than 12 weeks.

    • tunmi

      February 1, 2017 at 11:53 pm

      I hope he gets the funding. To me, this is good news. I look forward to seeing what happens

  4. Corolla

    February 2, 2017 at 12:33 am

    The sample size seems way too small. I say that the test it on a larger scale.

    Good steps in the right direction.

  5. Lucinda

    February 2, 2017 at 12:40 am

    I believe this news should generate more worldwide hype than it is at the moment. Something seems off.

  6. Engoz

    February 2, 2017 at 1:11 am

    It’s a good thing a Nigerian is involved in the drug discovery process. I’m just wondering if the clinical trial process is different in Nigeria. You can’t just write people who ‘volunteered’ to be tested on the drug in order to stylishly erase some ethical concerns. You said the laboratory findings have been published. Did he just jump from preclinical stage to sick patients? Don’t you have to test on healthy volunteers first for safety before jumping to the sick? What phase is the drug in in the clinical trial process for them to have it tested on HIV patients already? Is it phase 2,3? Many drugs pass through a phase and can’t even get pass the next phase. If you are seeking to pass this drug off internationally, you’d better start adhering to international standards. And BN you can’t write a cure has been discovered yet without answering these questions. You could have provided links to his published research articles.

  7. Fred

    February 2, 2017 at 1:55 am

    All these hate COS he’s Igbo. Pele God has made His choice and it cannot be changed. A chosen tribe is a blessed tribe. Pee in your pants if you want. Exactly why we need our own country.

    • Corolla

      February 2, 2017 at 3:37 am

      Only one idiot referenced tribe, yet you decided to focus on that one idiotic comment and write “all these hate”.

    • A Real Nigerian

      February 2, 2017 at 4:22 am

      Ahn ahn. Am I not your friend again?

    • No one

      February 2, 2017 at 6:59 am

      I don’t know why they just won’t let these ‘Biafrans’ go, so we can hear word. Y’all are so angry and I bet you’ll self destruct. Your ‘Biafra’ won’t last a decade.

  8. nunulicious

    February 2, 2017 at 3:25 am

    I can’t wait for this to be confirmed in a clinical trial. I am so glad that good news is coming from Nigeria. whoop whoop!

  9. LemmeRant

    February 2, 2017 at 7:59 am

    At least he’s doing something, which should be encouraged.
    So many professors out the are only interested in collecting 350k/month and lifelong pension.

  10. Ben

    February 2, 2017 at 8:20 am

    Give him enough security. Those pharmaceutical firms are lethal and nasty.

  11. Gravitas

    February 2, 2017 at 11:18 am

    Fred,you need to dump the tribal glasses you view the world with,so with some analysis and questions asked by people that understand the process better,like clinical tests,toxicity etc all you saw was tribe? Oga or madam,you need to do better in your approach to life issues
    Even A real Nigerian that decided to be a troll is Igbo,but of course you know ARN hates everything and everyone ,don’t you?

  12. isaid!!

    February 2, 2017 at 1:02 pm

    @ Ben, you are so right my brother. They should give him protection from the pharmaceutical companies. They are very dangerous o! Someone also discovered cure for diabetes, then they start “disappearing” Its not a joke o!

    • Sisi

      February 2, 2017 at 2:02 pm

      This is it!!! This is not a play play matter

  13. uche festus

    February 2, 2017 at 2:23 pm

    It is sure a good thing that he discovered a cure to the said ailment, one other thing he should be considerate about is the method of application and sides effect to the system.

  14. The Spectator

    February 3, 2017 at 7:07 am

    Wow! At least some took d initiative to do sumtin dat wil make d world a beta place. Dis is nothing but a great news! D test/side effects might actually be incomplete yet bt he’s almost there already. Kudos 2 u Prof! And whats up with this tribal issues? That’s barbaric!! I guess sum people are just tribal fanatics##GOD BLESS NIGERIA!

  15. Billy Joel

    October 27, 2017 at 4:38 am

    Why charge the sick so much money

  16. KATHERINE CHARLOTTE Arlene

    February 27, 2018 at 7:44 am

    Maduike Chiehiura Onwubiko Ezeibe, is a Professor of Veterinary Medicine and Clinical Virology at Michael Okpara University of Agriculture, Umudike, Nigeria. He holds a PhD from the University of Nigeria, Nsukka and is also a Fellow, College of Veterinary Surgeons, Nigeria (FCVSN).

    Prof. Ezeibe invented the Medicinal Synthetic Aluminum – Magnesium Silicate (Nano-medicine) – a broad-spectrum antiviral medicine, a highly active antiretroviral medicine, a potential anticancer medicine and adjuvant for antimicrobials. He also authored the book, The Medicinal Synthetic Aluminum-Magnesium Silicate {Al2 Mg3 (SiO4)3}. Also to his credit are 3 other patents, two other books and many scientific publications.

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